LOS ANGELES -- After being held homerless for his first 36 at-bats of the season, Manny Ramirez finally broke through with a solo home run in the first inning against the Rockies on Saturday.

Ramirez hit career home run No. 528 over the left-field fence on a 3-2 slider from right-hander Aaron Cook.

It marked Ramirez's first career home run against the Rockies, and he now has homered against all 30 active teams.

Ramirez became the 11th active player to have homered against all 30 clubs, joining Adrian Beltre, Russell Branyan, Mike Cameron, Tony Clark, Brian Giles, Troy Glaus, Jose Guillen, Gary Sheffield, Alfonso Soriano and Dmitri Young according to the Elias Sports Bureau.

"I'm glad I got it out of the way," Ramirez said. "I didn't think about it because I knew it was a long season. I knew I'd come around so I was just being patient."

Ramirez didn't wait long for his curtain call, homering in his second at-bat in the third inning to tie Honus Wagner for 19th all-time in RBIs with 1,732. It was his 54th multi-home run game to tie him with Frank Robinson for ninth on the all-time Major League list.

He didn't homer until his 12th game this season, but it wasn't his longest career homer drought to open a season. He didn't hit his first home run in 2006 until his 17th game when he hit two homers against the Blue Jays.