CLEARWATER, Fla. -- Phillies right-hander Roy Halladay struggled mightily Tuesday in a 10-6 loss to the Tigers at Bright House Field.

It could be cause for concern for the Phillies, who were counting on a healthy Halladay to bolster the rotation. He allowed a run in the first inning and two more in the second when Don Kelly hit a two-run home run to right-center field. Halladay continued to struggle in the third. He loaded the bases when he walked Victor Martinez, allowed a double to Alex Avila and hit Kelly with a pitch.

Ramon Santiago followed with a grand slam to right field in the third. The Tigers hit their third home run in the fifth, as Brayan Pena took Jake Diekman deep.

Halladay allowed six hits, seven runs, four walks, one wild pitch, two home runs, hit one batter and struck out two in 2 2/3 innings. He threw 69 pitches, leaving earlier than expected.

Tigers left-hander Drew Smyly allowed five hits, three runs (two earned), one walk and struck out one in 3 1/3 innings. They were the first runs that he's surrendered this spring.

For the Phillies, Ben Revere went 3-3 and Chase Utley had a homer and three RBIs.

Up next for Phillies: The Phillies play their first night game of the spring at 7:05 p.m. ET Wednesday against the Yankees at George M. Steinbrenner Field in Tampa. Phillies left-hander Cliff Lee gets the start. Right-handers Chad Durbin, Zach Miner, Mike Stutes and Justin De Fratus are scheduled to pitch. Stutes and De Fratus are competing for a spot in the Phillies bullpen. Watch the game live on MLB.TV.